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Which airway method saves more kids? major trial seeks answers

NCT ID NCT06364280

First seen Dec 08, 2025 · Last updated Jun 22, 2026 · Updated 27 times

Summary

This study tests three ways emergency crews help children breathe: a bag-mask, a throat tube, or a breathing tube. It includes 3,000 children with cardiac arrest, severe injury, or breathing failure. The goal is to see which method leads to more days alive and out of the ICU.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Children's National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Dell Medical School, University of Texas at Austin

    Austin, Texas, 78712, United States

  • Harbor-University of California Los Angeles Medical Center

    Los Angeles, California, 90509, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • Mecklenburg County Emergency Medical Services

    Charlotte, North Carolina, 28208, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • University of Airzona

    Tucson, Arizona, 85721, United States

  • University of California Davis

    Sacramento, California, 95817, United States

  • University of Colordao

    Aurora, Colorado, 80045, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bag-valve-mask ventilation, supraglottic airway, and endotracheal intubation

What this could lead to

If successful, this could identify the best emergency airway method for children, potentially saving more lives and reducing time in the ICU.

What could go wrong

The trial is currently suspended, and results may not apply to all children or settings. The study compares existing techniques, so no new treatment is being developed.

Conditions

The condition(s) this trial relates to.

cardiac arrest CHILD syndrome Critical Illness injury Out-of-Hospital Cardiac Arrest respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.