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New study tests Opioid-Free pain relief for breast surgery

NCT ID NCT06889870

Symptom relief Sponsor: Faculdade de Ciências Médicas de Minas Gerais Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a nerve block (PECS II) or local anesthesia works better for pain after breast cancer surgery, without using opioids. 124 women undergoing breast surgery were randomly assigned to receive one of the two methods. Researchers measured pain, nausea, and opioid use in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ropivacaine (local anesthetic) for nerve block or infiltration
What this could lead to
If PECS II block works better, it could offer a more effective, opioid-free way to manage pain after breast cancer surgery.
What could go wrong
This is a small, completed study, so results may not apply to all patients. Nerve blocks carry risks like infection or nerve damage, though rare.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

124 people

The number who actually took part.

Started

Apr 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:Female patients aged between 18 and 80 years, ASA physical status I, II or III and undergoing unilateral surgery. \- Exclusion Criteria: pregnant women, morbidly obese (BMI\>40 kg/m²), patients with cognitive impairment or inability to communicate with the evaluator, coagulopathies, history of allergy to local anesthetics and patients with a history of chronic pain or drug addiction. \-

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Conditions

The condition(s) this trial relates to.

agnosia breast cancer breast neoplasm Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia Pain Pain management

Contacts and locations

Locations

  • Hospital Nossa Senhora das Dores

    Itabira, Minas Gerais, Brazil

More trials for these conditions

Other studies related to the condition(s) this trial covers.