PCOS drugs may change your eyes – new study reveals
NCT ID NCT07419776
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study examined how common PCOS treatments (birth control pills and clomiphene citrate) affect the eyes. Researchers measured dry eye signs and retinal blood vessels in 60 women with PCOS and compared them to 30 healthy women. The goal was to see if these treatments cause changes in eye health over 6 months.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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90 people
The number who actually took part.
- Started
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Jun 2023
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
90 females, 30 of them with no previous medical or surgical history of importance 60 of them with confirmed laboratory and ultrasonography diagnosis of PCOS; 30 for cocps treatment and 30 for clomiphene citrate.
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Females at child bearing period (18-40 years old) * Patients recently diagnosed with polycystic ovarian syndrome.. Exclusion Criteria: * Patients who were diagnosed with Dry eye disease. * Patients who were treated with hormonal replacement therapy, Metformin, Aromatase inhibitors, clomiphene citrate or androgen antagonists. * Patients who underwent ocular surgeries. * patients with history of diabetes mellitus or hypertension.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kasr Alainy hospital
Cairo, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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