New hope for dangerous sugar crashes after gastric bypass

NCT ID NCT05928390

Ongoing Disease control Sponsor: RECORDATI GROUP Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 27 times

Summary

This study tests a drug called pasireotide to help people who have dangerously low blood sugar after weight-loss surgery. About 93 adults will receive either the drug or a placebo for 12 weeks, then everyone can get the drug for another 36 weeks. The goal is to see if pasireotide can stabilize blood sugar levels and reduce severe hypoglycemic episodes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AP-HP Hopital Europeen Georges Pompidou, 20, rue Leblanc,

Paris, 75015, France
Azienda Ospedale - Università Padova, Clinica Medica 3, Via Giustiniani, 2,

Padova, 35128, Italy
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

Palermo, Italy
Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita Cattolica del Sacro Cuore, L.go Gemelli 8

Rome, Italy
Guy's Hospital

London, United Kingdom
HCL Centre Hospitalier Lyon Sud

Pierre-Bénite, 69495, France
Hammersmith Hospital

London, W12 OHS, United Kingdom
Hopital Rangueil, Attachée de Recherche Clinique, Centre Investigation Clinique, CHU, Cedex 9, France

Toulouse, 31059, France
Hospital Clinic Barcelona, Lipid Clinic End, Nutr. Service Hospital Clinic, C. Villarroel, 170,

Barcelona, 08036, Spain
Hospital Clinico San Carlos, C/ Prof Martin Lagos s/n, Spain

Madrid, 28040, Spain
Hospital Germans Trias i Pujol

Barcelona, 08916, Spain
Hospital Universitari de Girona Dr. Josep Trueta

Girona, Spain
Hospital Universitario 12 de Octubre

Madrid, 28041, Spain
Hospital Universitario Reina Sofia

Córdoba, 14004, Spain
Hospital Universitario Vall d'Hebron, Passeig Vall d´Hebron 119-129, Spain

Barcelona, 08035, Spain
IRCCS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant Orsola

Bologna, 40138, Italy
Joslin Diabetes CenterJoslin Diabetes Center, One Joslin Place

Boston, Massachusetts, 02215, United States
King's College Hospital NHS Foundation Trust, Denmark Hill, SE5 9RS

London, EC1A 1AA, United Kingdom
Mayo Clinic - Rochester, 200 First Street, SW, 55905

Rochester, Minnesota, 55905, United States
Montefiore Medical Center, 111 E 210th Street,

The Bronx, New York, 10467, United States
NOLA Care

Metairie, Louisiana, 70006, United States
North Bristol NHS Trust

Bristol, BS10 5NB, United Kingdom
Northwestern University - Feinberg School of Medicine - Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, 60628, United States
Stanford University School of Medicine, Endocrinology, 800 Welch Road,

Palo Alto, California, 94305, United States
Universitaire Ziekenhuizen Leuven, Department of Gastroenterology and Hepatology,Herestraat 49

Leuven, 3000, Belgium
University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr,

San Antonio, Texas, 78229, United States
University of Wisconsin Health W. E. Clinic END, 451 Junction Rd,

Madison, Wisconsin, 53717, United States
Vanderbilt University Medical Center

Nashville, Tennessee, 37204, United States
Velocity Clinical Research - Annapolis

Annapolis, Maryland, 21401, United States

Conditions

Explore the condition pages connected to this study.

POST-BARIATRIC HYPOGLYCEMIA