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New hope for stoma patients: drug cuts dangerous fluid loss

NCT ID NCT02713776

First seen Dec 26, 2025 · Last updated May 20, 2026 · Updated 22 times

Summary

This study tested a drug called pasireotide in 57 adults who had bowel surgery and a stoma (enterostomy) that produced too much fluid, even after standard treatments. The goal was to see if pasireotide could reduce the amount of fluid lost through the stoma within 72 hours, helping patients avoid dehydration and kidney problems. Participants received either pasireotide or a placebo injection, and doctors measured the change in stoma output.

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Contacts and locations

Locations

  • Bordeaux Chu - Hopital Haut-Leveque

    Pessac, 33600, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • Centre Leon Berard

    Lyon, 69008, France

  • Chu Albert Michallon

    La Tronche, 38700, France

  • Chu Amiens-Picardie

    Amiens, 80054, France

  • Chu Caremeau

    Nîmes, 30029, France

  • Chu Estaing

    Clermont-Ferrand, 63003, France

  • Chu Marseille - Hopital Nord

    Marseille, 13 915, France

  • Chu Rouen Ch. Nicolle

    Rouen, 76031, France

  • Hopital Beaujon

    Clichy, 92110, France

  • Hopital Saint Antoine

    Paris, 75012, France

  • Hôpital Claude HURIEZ - CHRU Lille

    Lille, 59 067, France

  • Institut Regional Du Cancer Val D'Aurelle

    Montpellier, 34298, France

  • Toulouse - Chu Purpan

    Toulouse, 31059, France

Conditions

Explore the condition pages connected to this study.