New hope for ostomy patients: drug cuts dangerous fluid loss

NCT ID NCT02713776

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called pasireotide in 57 adults with high-output enterostomies (a surgically created opening in the belly) whose fluid loss was not controlled by standard treatments. The goal was to see if the drug could reduce the amount of fluid lost through the stoma within 72 hours, helping prevent dehydration and kidney problems. Participants received either pasireotide or a placebo injection, and researchers measured changes in output and the need for IV fluids.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bordeaux Chu - Hopital Haut-Leveque

    Pessac, 33600, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • Centre Leon Berard

    Lyon, 69008, France

  • Chu Albert Michallon

    La Tronche, 38700, France

  • Chu Amiens-Picardie

    Amiens, 80054, France

  • Chu Caremeau

    Nîmes, 30029, France

  • Chu Estaing

    Clermont-Ferrand, 63003, France

  • Chu Marseille - Hopital Nord

    Marseille, 13 915, France

  • Chu Rouen Ch. Nicolle

    Rouen, 76031, France

  • Hopital Beaujon

    Clichy, 92110, France

  • Hopital Saint Antoine

    Paris, 75012, France

  • Hôpital Claude HURIEZ - CHRU Lille

    Lille, 59 067, France

  • Institut Regional Du Cancer Val D'Aurelle

    Montpellier, 34298, France

  • Toulouse - Chu Purpan

    Toulouse, 31059, France