New pill design aims to smooth out Parkinson's drug levels
NCT ID NCT05471609
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tested a new oral version of the Parkinson's drug levodopa/carbidopa designed to release the medication slowly over time. Six healthy volunteers took the drug to see if it could keep steady levels in the blood. The goal is to reduce the 'on-off' motor fluctuations that many Parkinson's patients experience with standard pills.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- levodopa/carbidopa
- What this could lead to
- If successful, this formulation could help Parkinson's patients maintain more stable drug levels, potentially reducing motor fluctuations.
- What could go wrong
- This is a very early, small study in only 6 healthy people, not Parkinson's patients. It only measures drug levels, not actual symptom control, so real-world benefits are uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
-
6 people
The number who actually took part.
- Started
-
Jun 2025
- Finished
-
Aug 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Normal healthy * Are 18-65 years of age * Are not currently taking medications regularly * Able to fast 6 hours (water allowed) Exclusion Criteria: * Pregnancy * Inability to fast
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Minnesota
Minneapolis, Minnesota, 55455, United States
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