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New psychotherapy may ease chronic pain in veterans

NCT ID NCT07137715

Symptom relief Sponsor: University of Colorado, Denver Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a newer therapy called Pain Reprocessing Therapy (PRT) works better than standard Cognitive Behavioral Therapy (CBT) or usual care for veterans with chronic back or neck pain. About 360 veterans will be randomly assigned to one of three groups and complete questionnaires about their pain and health. Those in the PRT or CBT groups will have nine weekly video therapy sessions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Pain Reprocessing Therapy (PRT) and Cognitive Behavioral Therapy (CBT)
What this could lead to
If PRT works better than CBT or usual care, it could offer veterans a new, effective way to manage chronic back or neck pain without medication.
What could go wrong
This is a mid-sized trial comparing talk therapies, not a cure. Results may not apply to all pain types, and benefits may vary from person to person.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 360 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (18 and older) * Be veterans * Have a history of chronic back or neck pain defined as pain at least half the days of the last 6 months. * Have moderate or greater pain, defined as pain intensity ≥4 in the past week Exclusion Criteria: Clinical presentation suggestive of back pain that is secondary or peripheral in nature, including self-reported leg pain that is worse than back pain (indicative of radiculopathy or sciatica), spine surgery within the past 6 months, fall, motor vehicle accident or other trauma related to back pain in the past 6 months, back pain due to an inflammatory disorder, infection, or malignant etiology as determined per medical provider review, known sensory abnormality in trunk or legs, recent large (\>20 lbs) unexplained weight loss, difficulty controlling bowels (to screen out cauda equina syndrome), and self-reported diagnoses of specific inflammatory disorders (rheumatoid arthritis, polymyalgia rheumatica, scleroderma, Lupus, and polymyositis). Additionally, patients who meet any of the following criteria are ineligible due to anticipated difficulties complying with study procedures: * Moderate or severe cognitive impairment * Unstable or severe untreated mental health condition, including active suicidal ideation * Unstable or end-stage medical disease including active cancer * Back surgery planned within the next 6 months * Inability to communicate by telephone or video, including inability due to housing instability * Current pain-related litigation outside the VA (service connection-related applications are not excluded) * Having engaged in CBT or PRT for chronic pain in the past 6 months * Participants may be excluded based on the discretion of PIs Ashar and Frank

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Conditions

The condition(s) this trial relates to.

Back Pain Chronic Pain chronic pain syndrome Neck Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Back pain Back pain lower back chronic Chronic pain Neck pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • VA Eastern Colorado Health Care System

    RECRUITING

    Aurora, Colorado, 80045, United States

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Other studies related to the condition(s) this trial covers.