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Could a tiny nerve stimulator ease chronic pain without drugs?

NCT ID NCT06741579

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 28 times

Summary

This Stanford-led study tests whether adding a peripheral nerve stimulation (PNS) device to standard medical care can reduce chronic neuropathic pain in the lower back, pelvis, or legs. About 148 adults with long-term nerve pain will be randomly assigned to either standard care alone or standard care plus a wearable PNS device that sends electrical pulses to the nerve. The main goal is to see if more people in the device group achieve at least 50% pain relief after 3 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Stanford University

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Peripheral nerve stimulation device (SPR SPRINT PNS System)

What this could lead to

If successful, this could provide a non-drug option for people with chronic neuropathic pain to achieve significant pain relief.

What could go wrong

This is a mid-stage trial with 148 participants, so results may not apply to everyone. The device requires daily use and may not work for all types of pain.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.