Could a tiny nerve stimulator ease chronic pain without drugs?

NCT ID NCT06741579

Recruiting now Symptom relief Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This Stanford-led study tests whether adding a peripheral nerve stimulation (PNS) device to standard medical care can reduce chronic neuropathic pain in the lower back, pelvis, or legs. About 148 adults with long-term nerve pain will be randomly assigned to either standard care alone or standard care plus a wearable PNS device that sends electrical pulses to the nerve. The main goal is to see if more people in the device group achieve at least 50% pain relief after 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Peripheral nerve stimulation device (SPR SPRINT PNS System)
What this could lead to: If successful, this could provide a non-drug option for people with chronic neuropathic pain to achieve significant pain relief.
What could go wrong: This is a mid-stage trial with 148 participants, so results may not apply to everyone. The device requires daily use and may not work for all types of pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC NEUROPATHIC PAIN CHRONIC NEUROPATHIC PAIN (BELOW THE SHOULDERS) CHRONIC NEUROPATHIC PAIN IN THE LOW BACK AND LEGS PERIPHERAL NERVE STIMULATION

Contacts and locations

Locations

Stanford University
RECRUITING

Palo Alto, California, 94304, United States
The University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States

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