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New approach aims to ease chronic pain in breast cancer survivors without drugs

NCT ID NCT04531917

First seen Mar 23, 2026 · Last updated Jun 23, 2026 · Updated 12 times

Summary

This study tests whether combining pain neuroscience education (teaching patients about how pain works) with a gradual, timed increase in physical activity can reduce chronic pain in breast cancer survivors. About 122 survivors who have finished cancer treatment will be randomly assigned to either this combined program or usual care (an information leaflet). The goal is to see if the program lowers pain intensity and improves quality of life over three months, with follow-up lasting two years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Vrije Universiteit Brussel (VUB)

    Jette, Brussels Capital, 1090, Belgium

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pain neuroscience education and behavioural graded activity

What this could lead to

If it works, this could offer a non-drug way to manage chronic pain and improve quality of life for breast cancer survivors.

What could go wrong

This is a relatively small, early-stage trial (122 participants) testing a behavioural intervention, so results may not apply broadly. The effect may be modest, and long-term benefits are uncertain.

Conditions

The condition(s) this trial relates to.

breast neoplasm Chronic Pain chronic pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.