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Could a simple drug combo cut opioid use after lung surgery?

NCT ID NCT07359469

First seen Jan 23, 2026 · Last updated Jun 22, 2026 · Updated 22 times

Summary

This study examined whether giving lidocaine, ketamine, and magnesium during lung surgery helps reduce pain and the need for morphine afterward. Researchers followed 118 adults who had lung surgery and recorded their pain levels and opioid use. The goal was to see if this drug combination, already used in some hospitals, improves recovery without extra risks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Hospital Dr. Josep Trueta

    Girona, 17007, Spain

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lidocaine, ketamine, and magnesium (intravenous)

What this could lead to

If the results are positive, this could point toward a standard way to reduce pain and opioid use after lung surgery.

What could go wrong

This was an observational study, not a controlled trial, so it cannot prove cause and effect. The findings may not apply to all patients or surgical settings.

Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.