New study aims to ease Post-Mastectomy pain without opioids
NCT ID NCT07659990
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two types of nerve blocks given before modified radical mastectomy to see which provides better pain relief and reduces the need for strong painkillers. Eighty women scheduled for surgery will receive one of the two blocks, and researchers will track their pain scores, opioid use, and recovery quality. The goal is to find a safer, more effective way to manage pain after breast cancer surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block procedure
- What this could lead to
- If one block works better, it could mean less pain and fewer opioids after mastectomy, leading to a smoother recovery.
- What could go wrong
- This is a small, early-stage trial with only 80 participants. Results may not apply to all patients, and nerve blocks carry rare risks like infection or bleeding.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female patients aged 18-75 years * ASA physical status I-III * Scheduled for elective unilateral modified radical mastectomy with axillary dissection under general anesthesia * Provision of written informed consent Exclusion Criteria: * Anticoagulant therapy * Bleeding diathesis * Known allergy to local anesthetics or opioids * Infection at the block application site or previous surgery in the block area * Cognitive impairment preventing NRS assessment * Pregnancy or lactation * Chronic opioid use * Severe hepatic or renal failure * Refusal to participate in the study * Technical inability to perform the block or failed block
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Bursa City Hospital
RECRUITINGBursa, Nilüfer, 16100, Turkey (Türkiye)
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