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New pain block may cut opioid use after gallbladder surgery

NCT ID NCT07321639

Symptom relief Sponsor: Istanbul Medipol University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times

Summary

This study compares two ultrasound-guided nerve blocks—recto-intercostal fascial plane block (RIFPB) and transversus abdominis plane block (TAPB)—for pain control after laparoscopic gallbladder removal. 90 adults undergoing elective surgery will receive one of the two blocks. The main goal is to see which block reduces opioid painkiller use in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
local anesthetic (nerve block procedure)
What this could lead to
If one block works better, it could mean less pain and fewer opioids after gallbladder surgery.
What could go wrong
This is a small, early-stage comparison study. Results may not apply to other surgeries or patients, and individual pain responses vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Jan 2026

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ASA physical status I-II * Scheduled for elective laparoscopic cholecystectomy Exclusion Criteria: * Known allergy to local anesthetics or opioid medications * Infection at the planned block site * History of alcohol or drug dependence * Use of anticoagulant therapy * Refusal to participate in the study

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Conditions

The condition(s) this trial relates to.

Acute Pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute pain Laparoscopic cholecystectomy Pain management Plane blocks

Contacts and locations

Locations

  • Istanbul Medipol University

    Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.