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New nerve block may cut opioid use after gallbladder surgery

NCT ID NCT07276646

Symptom relief Sponsor: Zagazig University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two different nerve blocks to see which one better reduces pain and the need for strong painkillers after laparoscopic gallbladder removal. Eighty adults having elective surgery will be randomly assigned to receive one of the two blocks. The main goal is to see how long it takes before they need extra pain medication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nerve block procedure (retrosuperior costotransverse ligament block or erector spinae block)
What this could lead to
If successful, this could identify a better nerve block technique to reduce opioid use and improve pain control after gallbladder surgery.
What could go wrong
This is a small, early-phase study (80 participants) comparing two established techniques, so any advantage may be modest or not apply to other surgeries or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 64 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. patient acceptance 2. Age: 21-64 years old. 3. Sex: both sexes. 4. Physical status: ASA I \& II. 5. Body mass index (BMI): 18.5 - 30 kg/m2. 6. Type of operations: elective laparoscopic cholecystectomy. 7. Duration of surgery not more than 2 hours. Exclusion Criteria: 1. Known hypersensitivity to lidocaine or bupivacaine. 2. Patients with respiratory insufficiency. 3. Coagulation disorders or taking drugs affect surgical hemostasis. 7\. Patients with pre-existing neurological deficits. 8. Uncooperative patient or with altered mental status. 9. Patient with advanced cardiovascular or respiratory diseases

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Perioperative analgesia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of human medicine, Zagazig university, Zagazig

    RECRUITING

    Zagazig, Egypt

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