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New study aims to cut opioid use in gallbladder surgery with targeted nerve blocks

NCT ID NCT07595679

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will observe 80 adults having gallbladder surgery to compare two types of nerve blocks for pain control. One block targets the abdomen wall (M-TAPA), the other targets muscles between the ribs (external oblique intercostal). A skin sensor will guide how much opioid painkiller is needed during surgery. The goal is to see which block reduces opioid use more effectively.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nerve block (M-TAPA or external oblique intercostal plane block)
What this could lead to
If successful, this could help doctors choose the best nerve block to reduce opioid use during gallbladder surgery.
What could go wrong
This is a small observational study, not a randomized trial. Results may not apply to all patients or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients undergoing elective laparoscopic cholecystectomy under general anesthesia at a tertiary care hospital.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-80 years * ASA physical status I-III * Scheduled for elective laparoscopic cholecystectomy under general anesthesia * Ability to provide written informed consent Exclusion Criteria: * Patient refusal * Known allergy to local anesthetics * Chronic opioid use or opioid dependence * Neurological or psychiatric disorders affecting pain perception * Use of medications affecting autonomic nervous system activity, such as beta-blockers * Infection at the injection site * Coagulopathy or anticoagulant therapy * Pregnancy

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ankara etlik city hospital

    RECRUITING

    Ankara, Yenimahalle, Turkey (Türkiye)

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