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Tiny study sniffs out how oxycodone works in nose vs. mouth

NCT ID NCT07223450

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This completed Phase 1 trial tested how oxycodone moves through the body when given as a nose spray or an oral liquid. Eight healthy volunteers received a single dose of each form on separate days. The goal was to gather data to improve computer models that predict how drugs behave, not to treat any condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital del Mar Research Institute

    Barcelona, Spain

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oxycodone

What this could lead to

If successful, this could help create better computer models to predict how drugs like oxycodone work when given through the nose versus by mouth.

What could go wrong

This is a very small, early-phase study in healthy people, not patients. It only looks at drug levels, not treatment effects, so results may not apply to real-world use.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.