New test may spot hidden cancer cells in endometrial patients
NCT ID NCT06935305
First seen Nov 18, 2025 · Last updated Jun 20, 2026 · Updated 30 times
Summary
This study compares two methods—OSNA and ultrastaging—for finding cancer in lymph nodes removed during surgery for early-stage endometrial cancer. About 1,900 women will be randomly assigned to one of the two detection techniques. The goal is to see which method finds more cancer spread, which could help guide treatment decisions.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITINGRome, Italy, 00168, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If OSNA proves more accurate, it could help doctors better stage endometrial cancer and tailor treatments more precisely.
What could go wrong
This is a diagnostic comparison, not a treatment. Even if OSNA detects more metastases, it may not improve survival or change outcomes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.