New test may spot hidden cancer cells in endometrial patients
NCT ID NCT06935305
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two methods—OSNA and ultrastaging—for finding cancer in lymph nodes removed during surgery for early-stage endometrial cancer. About 1,900 women will be randomly assigned to one of the two detection techniques. The goal is to see which method finds more cancer spread, which could help guide treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If OSNA proves more accurate, it could help doctors better stage endometrial cancer and tailor treatments more precisely.
- What could go wrong
- This is a diagnostic comparison, not a treatment. Even if OSNA detects more metastases, it may not improve survival or change outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITINGRome, Italy, 00168, Italy
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