New combo aims to control tough lymphoma
NCT ID NCT06082102
First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 24 times
Summary
This study tests whether a new drug (orelabrutinib) plus rituximab works better than a standard combination (lenalidomide plus rituximab) for adults with marginal zone lymphoma that has come back or stopped responding to treatment. About 324 participants will receive one of the two combinations. The goal is to see which approach keeps the cancer from growing longer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beijing Tiantan Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100070, China
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Beijing Tongren Hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100730, China
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Fudan University Shanghai Cancer Center
RECRUITINGShanghai, Shanghai Municipality, 200040, China
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Guangdong Provincial Hospital of Chinese Medicine
RECRUITINGGuangzhou, Guangdong, 510120, China
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Henan Cancer Hospital
RECRUITINGZhengzhou, Henan, 450003, China
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Henan Provincial Peoples Hospital
RECRUITINGZhengzhou, Henan, 450003, China
Contact
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Hunan Cancer Hospital
NOT_YET_RECRUITINGChangsha, Hunan, 410000, China
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Jiangxi Cancer Hospital
RECRUITINGNanchang, Jiangxi, 330029, China
Contact
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510055, China
Contact
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The Affiliated Hospital Of Qingdao University
NOT_YET_RECRUITINGQingdao, Shandong, 266000, China
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The First Affiliated Hospital of Bengbu Medical College
RECRUITINGBengbu, Auhui, 233000, China
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The First Affiliated Hospital of Nanchang University
RECRUITINGNanchang, Jiangxi, 330006, China
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The First Affiliated Hospital of Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310003, China
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The Second Affiliated Hospital of Xi'an Jiaotong University（Xibei Hospital）
RECRUITINGXi’an, Shanxi, 710004, China
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The Second Hospital of Dalian Medical University
RECRUITINGDalian, Liaoning, 116023, China
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The first Hospital of China Medical University
RECRUITINGShenyang, Liaoning, 110002, China
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Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430000, China
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West China Hospital, Sichuan University
NOT_YET_RECRUITINGChengdu, Sichuan, 610041, China
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Yantai Yuhuangding Hospital
RECRUITINGYantai, Shandong, 264099, China
Contact
Conditions
Explore the condition pages connected to this study.