New combo therapy shows promise for Tough-to-Treat lymphoma
NCT ID NCT03533283
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 26 times
Summary
This study tests a combination of drugs (glofitamab, atezolizumab or polatuzumab vedotin, plus a single pre-treatment dose of obinutuzumab) in adults with B-cell non-Hodgkin's lymphoma that has come back or not responded to prior treatment. The goal is to find the safest dose and see how well the drugs shrink tumors. About 211 participants will take part across multiple centers.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Aarhus Universitetshospital Skejby
Aarhus N, 8200, Denmark
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Asst Papa Giovanni Xxiii
Bergamo, Lombardy, 24127, Italy
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Chaim Sheba Medical Center
Ramat Gan, 52621, Israel
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Fond. IRCCS Istituto Nazionale Tumori
Milan, Lombardy, 20133, Italy
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Hadassah Ein Karem Hospital
Jerusalem, 9112001, Israel
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Hospital Clinico Universitario Virgen de la Victoria
Málaga, 29010, Spain
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Hospital Clinico Universitario de Valencia
Valencia, 46010, Spain
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Hospital Duran i Reynals
Barcelona, 08907, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Istituto Nazionale Tumori Irccs Fondazione g. Pascale
Naples, Campania, 80131, Italy
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Odense Universitetshospital
Odense C, 5000, Denmark
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Policlinico S.Orsola-Malpighi
Bologna, Emilia-Romagna, 40138, Italy
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Rabin Medical Center-Beilinson Campus
Petah Tikva, 4941492, Israel
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Rigshospitalet
København Ø, 2100, Denmark
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START Madrid-FJD, Hospital Fundacion Jimenez Diaz
Madrid, 28040, Spain
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The HOPE Clinical Trials Unit
Leicester, LE1 5WW, United Kingdom
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The Newcastle upon Tyne Hospitals NHS Foundation Trust
Newcastle upon Tyne, NE1 4LP, United Kingdom
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UZ Gent
Ghent, 9000, Belgium
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University College London Hospitals NHS Foundation Trust
London, W1T 7HA, United Kingdom
Conditions
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