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Could a simple pill replace daily IV drips for skin infections?

NCT ID NCT00323219

Disease control Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether an oral antibiotic (moxifloxacin) works as well as a standard intravenous (IV) antibiotic (cefazolin) for treating moderate skin infections (cellulitis) in the emergency department. 390 patients with moderate cellulitis were treated either with daily IV antibiotics for 3-5 days or with oral moxifloxacin. The goal was to see if the oral option could be just as effective, potentially saving patients from daily hospital visits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
moxifloxacin (oral antibiotic) and cefazolin (intravenous antibiotic) with probenecid
What this could lead to
If oral moxifloxacin works as well as IV antibiotics, patients with moderate cellulitis could avoid daily hospital visits for IV treatment.
What could go wrong
This is a completed Phase 3 trial, so results are available. However, oral antibiotics may not be as effective for all types of infections, and some patients may still need IV therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

390 people

The number who actually took part.

Start date

Jan 2004

Finished

Dec 2013

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 18 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Cellulitis requiring outpatient intravenous antibiotic therapy; * ability to understand,/sign informed consent; * no contraindications to study medications, * not pregnant/breastfeeding Exclusion Criteria: \-

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Conditions

The condition(s) this trial relates to.

cellulitis Emergencies

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cellulitis

Contacts and locations

Locations

  • St. Paul's Hospital, Providence Healthcare, Emergency Medicine

    Vancouver, British Columbia, V1Y 1Z1, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.