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Gum treatment may clear up more than bad breath – study links oral health to smell

NCT ID NCT07424300

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 101 adults with gum disease and bad breath to see if treating the gums could also improve their sense of smell. Participants received standard deep-cleaning dental treatment. Researchers measured bad breath gases and smell function before and one week after treatment. The goal was to understand if reducing gum inflammation and bad breath is linked to better smelling ability.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nonsurgical periodontal therapy (scaling and root planing)
What this could lead to
If successful, this could show that treating gum disease improves both bad breath and sense of smell, pointing to a connection between oral health and olfactory function.
What could go wrong
This is a small, completed observational study, not a treatment trial. Results may not apply to everyone, and any changes in smell could be due to other factors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

101 people

The number who actually took part.

Started

Dec 2024

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of adults aged 18-55 years diagnosed with generalized periodontitis and presenting with complaints of halitosis who sought care at the Batman University Faculty of Dentistry Clinical Application Center. A total of 150 patients were screened, and 101 individuals who met the inclusion criteria were enrolled in this prospective cohort study.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion Criteria: * Adults aged 18-55 years * Diagnosis of generalized periodontitis * Complaint of halitosis * At least 15 natural teeth Exclusion Criteria: * Self-reported smell loss or change within 2 weeks prior to baseline * Antibiotic or anti-inflammatory drug use for more than 7 days within the previous 6 weeks * Presence of upper respiratory tract infection * Unrestored advanced dental caries * History of COVID-19 infection * Pregnancy Smoking was not an exclusion criterion.

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Conditions

The condition(s) this trial relates to.

Halitosis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Batman University

    Merkez, Batman, 72040, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.