Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New strategy aims to cut risks when emergency breathing tubes are needed

NCT ID NCT05539391

Disease control Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a combined approach for emergency breathing tube insertion in adults outside the hospital. The strategy includes a muscle relaxant (rocuronium), mask ventilation before intubation, and a special guide (gum elastic bougie). Researchers will compare complication rates in 1,500 patients to see if this method reduces severe events like cardiac arrest or low oxygen.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
rocuronium
What this could lead to
If successful, this could establish a safer standard method for emergency intubation, reducing life-threatening complications like cardiac arrest or low oxygen.
What could go wrong
This is a cluster trial with no blinding, so results may be influenced by how teams follow the protocol. The strategy may not work for all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2023

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient adult (≥ 18 years) presenting with vital distress requiring emergency tracheal intubation as assessed by the emergency physician in the out-of-hospital setting. * Patient with all conditions (trauma, dyspnea, coma, overdoses, and shock) except those in cardiac arrest will be included. Exclusion Criteria: * Patient presenting of a contraindication to succinylcholine, and/or rocuronium, and/or sugammadex (rocunorium antagonist). * Patient who have contraindication to bag face mask ventilation before intubation (ongoing emesis, hematemesis, or hemoptysis). * Patient that are not members of a medical aid scheme (beneficiary or main member). * Patient under specific protection measures: pregnant, parturient or nursing women; legal protection or deprived of liberty: patient under judicial protection, patient under guardianship/curatorship.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Emergencies are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Emergencies

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Emergencies Out-of-hospital setting Tracheal intubation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    22 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AP-HP - Hôpital Avicenne

    RECRUITING

    Bobigny, 93000, France

  • AP-HP - Hôpital Henri Mondor

    RECRUITING

    Créteil, 94000, France

  • AP-HP - Hôpital Lariboisière

    RECRUITING

    Paris, 75013, France

  • AP-HP - Hôpital Necker

    RECRUITING

    Paris, 75730, France

  • AP-HP - Hôpital Pitié-Salpétrière

    RECRUITING

    Paris, 75013, France

  • AP-HP - Hôpital Raymond Poincaré

    RECRUITING

    Garches, 92380, France

  • CH Carnelle Portes de l'Oise

    RECRUITING

    Beaumont-sur-Oise, 95260, France

  • CH de Pontoise René Dubos

    RECRUITING

    Cergy-Pontoise, 95303, France

  • CH de Versailles - Site André Mignot

    NOT_YET_RECRUITING

    Le Chesnay, 78157, France

  • CHU Poitiers - Hôpital la Milétrie

    RECRUITING

    Poitiers, 86021, France

  • CHU Toulouse - Hôpital Purpan

    RECRUITING

    Toulouse, 31059, France

  • CHU d'Angers

    RECRUITING

    Angers, 49933, France

  • CHU de Bordeaux - Hôpital Pellegrin

    RECRUITING

    Bordeaux, 33000, France

  • CHU de Dijon

    NOT_YET_RECRUITING

    Dijon, 21000, France

  • CHU de Grenoble - Hôpital Nord La Tronche

    RECRUITING

    La Tronche, 38700, France

  • CHU de Montpellier Site Lapeyronie

    RECRUITING

    Montpellier, 34000, France

  • CHU de Nantes - Hôpital Hôtel Dieu

    RECRUITING

    Nantes, 44093, France

  • CHU de la Réunion - site Sud

    RECRUITING

    Saint-Pierre, 97448, France

  • GH Eaubonne Montmorency Hôpital Simone VEIL

    RECRUITING

    Eaubonne, 95600, France

  • GH Sud Ile de France

    RECRUITING

    Melun, 77000, France

  • GH Sélestat Obernai

    NOT_YET_RECRUITING

    Sélestat, 67 600, France

  • HCL - Hôpital Edouard Herriot

    RECRUITING

    Lyon, 69003, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.