EMERGENCIES

This study tests whether sending high-risk infants home with a special pulse oximeter (Owlet OSS 3.0) after NICU discharge can reduce emergency room visits and serious rehospitalizations. About 700 babies who no longer need oxygen support will be randomly assigned to standard car…

This study tests a combination of techniques to make emergency breathing tube insertion safer for adults in life-threatening situations. The strategy includes using a muscle relaxant, giving oxygen through a mask before the procedure, and using a special guide for the tube. Resea…

This study tests whether a lower dose (15mg) of the painkiller ketorolac works as well as a higher dose (30mg) for kidney stone pain in the emergency room. About 86 adults under 65 with moderate to severe pain will be enrolled. Researchers will measure pain levels over several ho…

This study looks at whether wearing a lumbar brace for 4 weeks after an ER visit for low back pain can lower pain, improve spine function, and reduce the need for painkillers. About 152 adults aged 18-65 in Edmonton will be enrolled. The goal is to find a safer, non-drug option f…

This study looks at whether patients who take antiplatelet drugs (like aspirin) and have a minor head injury but no other signs of brain bleeding can safely skip a CT scan. Current guidelines often send these patients for a scan, but the benefit is unclear. Researchers will follo…

This study tracks how a small amount of glucose spreads in the body of adults with severe burns (covering at least 30% of skin) during their first four days in intensive care. Researchers measure glucose levels before and after a quick injection to calculate the initial distribut…

This study is testing whether connecting ambulances carrying seriously ill children to a remote doctor via a simple audio-video device can improve medical decisions and health outcomes. The trial will take place in Karachi, Pakistan, with 900 children. One group will receive a te…

This study aims to create a simple tool (called a nomogram) that helps doctors predict whether a laparoscopic appendix removal will be difficult. Researchers will look at information from 500 patients who had the surgery, such as test results and patient details, to find clues th…

This study looks at a new method to deliver fentanyl, a strong painkiller, by breathing it in through the nose or a face mask. It involves 20 healthy adults to see how well the medicine is absorbed and how comfortable the method is. The goal is to find a faster, needle-free way t…