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Timing matters: study seeks optimal moment for cervical length check to prevent preterm birth

NCT ID NCT06822647

Knowledge-focused Sponsor: Henry Ford Health System Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to find the best time to measure cervical length during a standard pregnancy ultrasound (anatomy scan) to improve accuracy. Researchers will compare measurements taken at the start versus the end of the scan in 550 pregnant individuals. They will also test if a special sepia filter on the ultrasound machine helps get clearer images. The goal is to better identify those at risk for preterm birth.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could establish a best practice for when to measure cervical length during pregnancy scans, potentially improving detection of preterm birth risk.
What could go wrong
This is an early-stage procedural study, not testing a new treatment. Results may not change clinical practice if the timing difference is minimal or not reproducible in other settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 550 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pregnant individuals between 16 weeks and 23 weeks + 6 days of gestation. * Presenting for a fetal anatomy survey at Henry Ford Health MFM ultrasound units. * Consent to a transvaginal cervical length measurement as part of routine care. * Agreement to participate in the study, including randomization for the timing of cervical length measurement. Exclusion Criteria: * History of preterm delivery. * Diagnosis of cervical insufficiency. * Declines or unable to consent to a transvaginal cervical length measurement. * Patients receiving care at non-Henry Ford Health radiology clinics.

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Conditions

The condition(s) this trial relates to.

cervical incompetence Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervical insufficiency Cervical length measurement Preterm birth

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Henry Ford Health New Center One

    RECRUITING

    Detroit, Michigan, 48202, United States

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