Head position showdown: flat or elevated after stroke?
NCT ID NCT07507097
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two common head positions—lying flat (0°) versus raising the head 30°—for the first 24 hours after a severe ischemic stroke. Researchers want to see which position leads to better recovery and fewer complications. About 1,500 adults with severe stroke will be randomly assigned to one of the two positions. The goal is to find a simple, safe nursing practice that improves long-term outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If it works, this could establish a simple, low-cost nursing standard to improve outcomes after severe stroke.
- What could go wrong
- This is an early-stage study comparing two routine positions; results may show no clear benefit or be limited to specific patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,508 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria 1. Age ≥ 18 years 2. Meeting the diagnostic criteria for acute ischemic stroke according to the "Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2023": ①Acute onset, ②Focal neurological deficits, with a few having global neurological deficits, ③Imaging shows a corresponding lesion or symptoms/signs persist for more than 24 hours, ④Exclusion of non-vascular causes, ⑤Brain CT/MRI excludes cerebral hemorrhage 3. Meeting the criteria for severe ischemic stroke patients: severe neurological deficits at admission \[for example, National Institutes of Health Stroke Scale (NIHSS) score≥15\] 4. First-time diagnosed ischemic stroke patients who undergo thrombolysis and/or thrombectomy reperfusion treatment 5. Time from onset to randomization within 24 hours 6. Informed consent obtained and signed by the patient or their family Exclusion Criteria 1. Known pregnancy or breastfeeding, or positive pregnancy test before randomization 2. Expected survival time less than 3 months (such as with malignant tumors, severe cardiopulmonary diseases, etc) 3. Already participating in other interventional clinical studies that may affect outcome assessment 4. Other situations deemed by the investigator as unsuitable for participation in this study or that may pose significant risks to the patient (such as inability to understand and/or comply with study procedures and/or follow-up due to mental illness, cognitive or emotional disorders) 5. Presence of brain midline shift or herniation, ventricular mass effect 6. Patients with limited head elevation (or patients unable to cooperate with postural intervention due to their condition/recovery needs, etc.) 7. Presence of respiratory infection symptoms such as fever, cough, or sputum production at the time of admission
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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West China Hospital, Sichuan University
Chengdu, Sichuan, 610041, China
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