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Brain scans reveal hidden impact of opioid overdoses

NCT ID NCT05651516

First seen Jan 11, 2026 · Last updated Jun 10, 2026 · Updated 28 times

Summary

This study looked at whether opioid use disorder and non-fatal overdoses cause a harmful protein called tau to build up in the brain. Researchers used special PET/CT scans on 12 adults, including those with opioid use disorder and healthy volunteers. The goal was to understand long-term brain changes, not to test a treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

The condition(s) this trial relates to.

opiate dependence Pick disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.