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Keyhole surgery vs. open surgery for pancreatic cancer: which is safer?

NCT ID NCT07328607

First seen Jan 11, 2026 · Last updated Jun 23, 2026 · Updated 24 times

Summary

This study compares two types of Whipple surgery for people with pancreatic or nearby cancers: the traditional open surgery and a newer keyhole (laparoscopic) approach. About 90 adults with resectable tumors will be randomly assigned to one of the two procedures. The goal is to see if the laparoscopic method is as safe and effective as the standard open surgery, especially in terms of complications and recovery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Liver and GIT hospital , Minia University

    RECRUITING

    Minya, Minya Governorate, 61519, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Surgical procedure (open or laparoscopic pancreaticoduodenectomy)

What this could lead to

If successful, this could show that laparoscopic Whipple surgery is as safe as open surgery, potentially leading to faster recovery and shorter hospital stays for patients.

What could go wrong

This is a single-center trial with only 90 participants, so results may not apply broadly. Laparoscopic surgery is complex and may carry higher risks of complications in some patients.

Conditions

The condition(s) this trial relates to.

Adenoma, Islet Cell carcinoma of the ampulla of vater distal biliary tract carcinoma duodenal adenocarcinoma pancreatic ductal adenocarcinoma pancreatic neuroendocrine tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.