Scientists investigate whether autoantibodies drive obesity
NCT ID NCT07542327
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether certain autoantibodies (proteins that mistakenly attack the body) are more common in people with obesity and if they are linked to related health problems like type 2 diabetes. Researchers will study 160 adults with a BMI over 30. The goal is to better understand the role of these antibodies, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 160 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The South Danish Obesity Initiative (SDOI) cohort. This is an ongoing clinical initiative offering screening of a broad panel of obesity related diseases to individuals with BMI above 30 kg/m² and age between 18 and 60 years. People are referred from their general practitioners or from hospital departments and undergo screening for diabetes, dyslipidemia, obstructive sleep apnea, metabolic associated steatohepatitis and hypertension. In addition, a cohort of people with BMI 18.5 to 30 kg/m² has been assessed with an identical screening program with the purpose of serving as a control group. Only participants who gave informed consent to use their data for research purposes are included in this study.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Inhabitant in the Region of Southern Denmark * BMI above 30kg/m2 * age between 18 and 60 years. Exclusion Criteria: * individuals previously treated with GLP-1RA medication for any indication * Individuals who have previously undergone bariatric surgery * Individuals with type 1 diabetes
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University Hospital of Southern Denmark, Esbjerg
Esbjerg, Region Syddanmark, 6700, Denmark
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