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New heart valve delivery system shows promise in 137-Patient trial

NCT ID NCT05478161

First seen Nov 17, 2025 · Last updated May 23, 2026 · Updated 32 times

Summary

This study tested a new system (IMPERIA) for delivering a replacement heart valve (ALLEGRA) in 137 people with severe aortic stenosis or a failed surgical valve. The main goal was to see if the valve was placed correctly and worked well 7 days after the procedure. The study focused on safety and performance, not on curing the underlying condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Catharina Hospital

    Eindhoven, Netherlands

  • Erasmus Medical Center

    Rotterdam, Netherlands

  • Herz- und Gefäßzentrum Bad Bevensen

    Bad Bevensen, Germany

  • Hospital Alvaro Cunqueiro

    Vigo, 36213, Spain

  • Hospital Clínico San Carlos

    Madrid, Spain

  • Hospital Universitari de Bellvitge

    Barcelona, Spain

  • Hospital Universitario Virgen de la Victoria

    Málaga, Spain

  • Hospital Universitario de Salamanca

    Salamanca, Spain

  • Maastricht University Medical Center

    Maastricht, Netherlands

  • Schüchtermann Klinik

    Bad Rothenfelde, Lower Saxony, 49214, Germany

  • UKSH, Campus Lübeck

    Lübeck, Germany

Conditions

Explore the condition pages connected to this study.