New strategy may cut unnecessary pacemakers after heart valve procedure
NCT ID NCT07414485
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new way to predict dangerous heart rhythm problems after a common heart valve procedure called TAVR. Researchers combined ECG results with CT scan measurements and implant depth to see if they could safely identify low-risk patients. The study looked back at 209 patients who had TAVR and were sent home without a pacemaker, tracking who later needed one within three months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this approach could help doctors safely avoid implanting unnecessary pacemakers in many patients after TAVR, reducing procedure risks and healthcare costs.
- What could go wrong
- This is a retrospective, observational study, not a randomized trial, so the findings may not apply to all patients. The strategy needs prospective validation before changing clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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209 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consisted of 209 consecutive patients underwent TAVR using contemporary transcatheter valve prostheses and were managed according to a standardized ECG-based post-procedural conduction monitoring algorithm. Only patients without pre-existing permanent pacemaker implantation and without immediate post-procedural indication for permanent pacing were included in the analysis. This population represents a clinically relevant group in whom post-discharge conduction risk stratification is particularly challenging and in whom optimization of monitoring strategies is most impactful.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Any patient aged over 18 years * underwent TAVI, regardless of the access route and valve type * discharged from the hospital without a pacemaker Exclusion Criteria: * Patients with a pre-existing pacemaker prior to TAVI
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculté de médecine montpellier
Montpellier, 34090, France
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Other studies related to the condition(s) this trial covers.
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