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Nurses take the lead: new study tests Nurse-Run chest pain diagnosis in emergency rooms

NCT ID NCT06149819

Diagnosis Sponsor: University Hospital, Grenoble Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing whether specially trained nurses can safely diagnose non-traumatic chest pain in the emergency department using a step-by-step guide based on medical recommendations. About 182 adults with chest pain will be split into two groups: one managed by nurses using the new pathway, and one receiving usual care from doctors. The goal is to see if the nurse-led approach is just as safe and effective, which could lead to faster care and less strain on emergency doctors.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
nurse-led diagnostic pathway
What this could lead to
If successful, this could show that specially trained nurses can safely and effectively manage chest pain in the emergency department, potentially speeding up care and freeing up doctors.
What could go wrong
This is a small pilot study (182 people) at one hospital, so results may not apply everywhere. It tests a process, not a new drug, so the impact is limited to how care is delivered.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 182 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2023

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Admission to emergency department (ED) for non-traumatic Chest Pain * Affiliation to the French social security system * Written informed consent must be obtained * For women of childbearing age: effective contraception in place for at least 3 months. The absence of pregnancy should be confirmed by a negative urine test without delaying the start of the management including the realization of Electrocardiogram (EKG/ECG). Exclusion Criteria: * Suspected alcohol, drug or toxic intoxication * Chest pain with associated neurological signs * Patient with pacemaker or defibrillator * Patient in vital distress requiring immediate medical intervention * Patient admitted with a previously established aetiological diagnosis * Unable to communicate or non-french speaking patients or those with impaired comprehension or consciousness * Pregnant or breast-feeding patients * Subject under administrative or judicial control, under protection

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Conditions

The condition(s) this trial relates to.

Chest Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chest pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU Grenoble Alpes

    RECRUITING

    Grenoble, Grenoble, 38043, France

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