One blood test to rule out heart attacks?
NCT ID NCT01334645
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study is testing whether measuring a protein called copeptin in the blood, alongside the standard troponin test, can help doctors quickly rule out a heart attack in people arriving at the emergency room with chest pain. Participants with chest pain that started within the last 12 hours will have blood samples taken over several hours to measure copeptin, troponin, and other markers. The goal is to see if a normal copeptin and troponin result can safely exclude a heart attack without the need for prolonged monitoring and repeated blood tests.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Copeptin blood test
- What this could lead to
- If it works, this could lead to faster, simpler diagnosis of heart attacks, reducing the need for prolonged monitoring and repeated blood draws.
- What could go wrong
- This is a small, early-stage diagnostic study. The test may not prove accurate enough to replace current methods, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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134 people
The number who actually took part.
- Start date
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Mar 2011
- Finished
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Mar 2012
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Chest pain suggestive of Acute Coronary Syndrome * Chest pain with onset within the last 12 h * Patients older than 18 years Exclusion Criteria: * ST-Elevation Myocardial infarction * Legal incapacity * Sepsis * Hyponatremia \< 135 mmol/L * Shock * Lung neoplasms * life expectancy of less than 6 months * Refuse to consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France
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