AI could sharpen emergency diagnoses for chest pain and breathing trouble
NCT ID NCT07727590
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial tests whether an artificial intelligence tool can help emergency room doctors better diagnose patients with chest pain, shortness of breath, or other acute heart and lung symptoms. The AI analyzes ECGs, chest X-rays, lab results, and patient history to suggest possible diagnoses. About 1,000 adults across multiple hospitals will be randomly assigned to receive either standard care or AI-assisted diagnosis. The goal is to see if the AI improves how often the emergency diagnosis matches the final confirmed diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A GPT-based multimodal visual language model that analyzes ECGs, chest X-rays, lab results, and patient history to suggest diagnoses.
- What this could lead to
- If successful, this AI tool could help emergency doctors make faster, more accurate diagnoses for common but serious symptoms like chest pain and shortness of breath.
- What could go wrong
- The AI may not improve accuracy in real-world emergency settings, could produce errors, or may not work equally well for all patient groups. This is an early-stage trial.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2027
An estimate. Start dates often move.
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years * Presentation to a participating emergency department with acute cardiopulmonary symptoms, including chest pain, dyspnea, palpitations, syncope, dizziness, or fever accompanied by cardiopulmonary symptoms * Performance of both a standard 12-lead electrocardiogram and chest radiography during the initial emergency department evaluation * Availability of initial clinical assessment, vital signs, laboratory findings, and all mandatory clinical information required for the multimodal AI workflow * Expected emergency department observation or hospital admission for at least 24 hours * Ability and willingness to provide written informed consent Exclusion Criteria: * Inability or refusal to provide written informed consent * Requirement for immediate life-saving intervention that precludes completion of the study workflow * Death before completion of the initial emergency department diagnostic assessment * Electrocardiographic quality insufficient for reliable physician or Artificial intelligence (AI) interpretation * Chest radiographic quality insufficient for reliable physician or Artificial intelligence (AI) interpretation * Cardiac pacing rhythm * Missing mandatory clinical information required for the multimodal Artificial intelligence (AI) workflow * Previous enrollment in the ER-VISION-AI trial * Inability to establish a blinded adjudicated reference diagnosis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ewha Womans University Mokdong Hospital
Seoul, 07804, South Korea
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