Can a simple finger sensor predict tissue health in septic shock?
NCT ID NCT07330908
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether the dose of norepinephrine, a drug used to raise blood pressure, changes how well a non-invasive finger sensor (peripheral perfusion index) can predict tissue health in 80 septic shock patients. Researchers compared two dose levels to see if the sensor's accuracy varied. The goal is to find better ways to monitor critically ill patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- norepinephrine
- What this could lead to
- If successful, this could help doctors better monitor tissue health in septic shock patients, potentially improving treatment decisions.
- What could go wrong
- This is a small, completed study with only 80 participants. Results may not apply to all patients, and the findings are about monitoring, not a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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80 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Mar 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 to 65 years. * Both sexes. * Septic shock patients requiring norepinephrine infusion at dose \<0.25 µg/kg/min to achieve mean arterial pressure (Mean arterial blood pressure ≥ 65 mm Hg). Exclusion Criteria: * Patients fail to achieve Mean arterial blood ≥ 65 mm Hg or need norepinephrine dose ≥0.25 µg /kg/min. * Pregnancy. * Diabetes mellitus. * Tissue edema. * Respiratory diseases affecting gas exchange, such as asthma and Chronic Obstructive Pulmonary Disease. * Sever hypoxemia or hypercarbia. * Core temperature \< 36 ᴼc. * Body mass index ≥35 kg/m2 * Cardiovascular diseases and pulmonary edema
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Tanta University
Tanta, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Chilling fever: can cooling septic shock patients save lives?
- Bedside eye scans may reveal hidden blood flow problems in septic shock
- Can two blood markers catch sepsis before it turns deadly?
- Two cheap blood ratios put to the test as sepsis death predictors
- Can a bedside ultrasound predict which septic shock patients will stop breathing on their own?
- Can a computer model speed up sepsis blood tests?