Can big data unlock the secrets of a deadly aortic emergency?
NCT ID NCT06862583
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This study gathers detailed information from thousands of patients across Nordic countries and the Netherlands who have acute type A aortic dissection, a rare and life-threatening tear in the aorta. Researchers will track patients' health before surgery, the surgical procedure they receive, and their short- and long-term outcomes, including survival and need for further procedures. The goal is to identify risk factors and better surgical strategies to improve survival and reduce complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Open heart surgery or aortic endovascular intervention
- What this could lead to
- If successful, this could identify risk markers to guide preventive surgery and improve surgical techniques, potentially reducing deaths from this rare but often fatal emergency.
- What could go wrong
- This is an observational registry study, not a controlled trial, so it cannot prove cause and effect. Results may be limited by differences in care across centers and the complexity of the condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Jun 2019
- Expected to finish
-
Jun 2030
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All patients with acute type A aortic dissection referred to any of the participating centers
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Acute (within 14 days of onset) type A aortic dissection or similar acute aortic syndrome Exclusion Criteria: * Age \<18 years at onset
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Aortic dissection are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Karolinska Institute
RECRUITINGStockholm, SE17177, Sweden
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a patch seal the leak after aortic repair? a new device aims to find out
- Massive chest pain registry reveals gaps between guidelines and real-world care in china
- New registry aims to unlock mysteries of Pregnancy-Related aortic tears
- Massive study aims to settle best surgery for deadly aortic tear
- New Stent-Graft procedure offers hope for High-Risk aortic patients
- Tailored surgery may save lives in aortic dissection