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Deep cleaning showdown: one session or three for gum disease?

NCT ID NCT07272980

Disease control Sponsor: Gülnur Emingil Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether splitting deep cleaning into three sessions works better than doing it all at once for people with severe gum disease. 48 non-smoking adults with advanced periodontitis were randomly assigned to one of the two cleaning methods. Researchers checked gum health, inflammation markers, and bacteria levels over 6 months to see which approach leads to better outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

Nov 2010

Finished

May 2011

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Systemically healthy, non-smoking individuals aged 18-65 years * Diagnosis of Stage III or IV Grade C periodontitis according to the 2018 classification of periodontal diseases * Presence of at least 20 teeth * No periodontal treatment within the previous 6 months * Willingness to participate and provide written informed consent Exclusion Criteria: * Presence of systemic diseases or conditions affecting the periodontium (e.g., diabetes mellitus, cardiovascular diseases, immunological disorders) * Pregnancy or lactation * Use of antibiotics, anti-inflammatory, or immunosuppressive drugs within the past 3 months * History of periodontal therapy or surgery within the last 6 months * Smoking or use of any tobacco products

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Conditions

The condition(s) this trial relates to.

periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontitis (stage 3) Periodontitis stage III

Contacts and locations

Locations

  • Istinye University, School of Dentistry

    Istanbul, Turkey, 34408, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.