Could a simple CT scan be enough to decide stroke treatment?
NCT ID NCT05230914
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a simple CT scan (NCCT) works as well as advanced imaging (CTP/MRI) for choosing stroke patients who need emergency clot removal. About 1,846 adults with acute stroke arriving within 24 hours of symptoms will be enrolled. The goal is to see if the simpler method leads to similar recovery outcomes at 90 days.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,846 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Aged 18 years or older; 2. The interval time from last known well to hospital arrival is within 24 hours; 3. Acute stroke confirmed by clinical symptoms or imaging examination; 4. Field Assessment Stroke Triage for Emergency Destination (FAST ED) ≥4; 5. Written informed consent is obtained from patients and/or their legal representatives. Exclusion Criteria: 1. Allergy to radiographic contrast agents, or nitinol devices; 2. Currently pregnant or lactating (women patients); 3. Arterial tortuosity and/or other arterial disease that would prevent the device from reaching the target vessel; 4. Preexisting neurological or psychiatric disease that would confound the neurological functional evaluations; 5. Multiple vessel occlusion (e.g., bilateral anterior circulation, or occlusion of both anterior and posterior circulation); 6. Brain tumors with mass effect (except meningiomas) that are radiographically pleasant; 7. Intracranial aneurysm, arteriovenous malformation; 8. Any terminal illness with life expectancy less than 6 months; 9. Unlikely to be available for 90-day follow-up.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
8 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Dalian Central Hospital
RECRUITINGDalian, Liaoning, 116000, China
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Huai'an First People's Hospital
RECRUITINGHuai'an, Jiangsu, 223001, China
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Jingdezhen First People's Hospital
RECRUITINGJingdezhen, Jiangxi, 333000, China
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The 904th Hospital of CPLA
NOT_YET_RECRUITINGWuxi, Jiangsu, 214000, China
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The First Affiliated Hospital of Hainan Medical University
RECRUITINGHaikou, Hainan, 570000, China
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Wuyi Traditional Chinese Medicine Hospital
NOT_YET_RECRUITINGJiangmen, Guangdong, 529000, China
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Xinqiao Hospital of Army Medical University
NOT_YET_RECRUITINGChongqing, Chongqing Municipality, 400037, China
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Yijishan Hospital of Wannan Medical College
RECRUITINGWuhu, Anhui, 241000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Stroke's hidden heart rhythm clue under investigation
- After a stroke, does the heart inflame? MRI study probes the link
- Natural capsule tested as Add-On for stroke recovery
- Robots and brain scans team up to find stroke Recovery's master switch
- Can a drug infused into brain arteries protect stroke patients during clot removal?
- Can a Clot-Busting drug help stroke patients treated later?