Blood test may predict kidney danger in muscle injury patients
NCT ID NCT01544231
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 197 emergency room patients with rhabdomyolysis (severe muscle breakdown) to see if a blood test for a protein called NGAL could predict who would develop acute kidney failure within 48 hours. The goal is to help doctors identify high-risk patients earlier and start treatment faster.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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197 people
The number who actually took part.
- Start date
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Aug 2013
- Finished
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Dec 2015
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with suspected rhabdomyolysis admitted to the participating University Hospital emergency rooms (see inclusion/exclusion criteria).
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The patient must have given his/her informed and signed consent * The patient must be insured or beneficiary of a health insurance plan * Patient hospitalized with Creatine Phospho-Kinase \> 1000 UI/l Exclusion Criteria: * The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is under judicial protection, under tutorship or curatorship * The patient refuses to sign the consent * It is impossible to correctly inform the patient * The patient is pregnant, parturient, or breastfeeding * Chronic renal insufficiency with dialysis * The patient has an acute coronary syndrome * Nephrotoxic medications within 72 hours prior to admission * Need for a procedure involving the injection of iodine * Patient in shock * Occurrence of acute renal failure can be explained by a cause other than rhabdomyolysis.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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APHP - Groupe Hospitalier Pitié-Salpetrière
Paris, 75651, France
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CHU de Montpellier - Hôpital Lapeyronie
Montpellier, 34295, France
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CHU de Nice - Hôpital St-Roch
Nice, 06006, France
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CHU de Nîmes - Hôpital Universitaire Carémeau
Nîmes, Gard, 30029, France
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Hôpital Interarmées Sainte Anne
Toulon, 83800, France
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