Gene therapy shot aims to tame wet AMD
NCT ID NCT05984927
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 15 times
Summary
This early-stage study tests a gene therapy called NG101 for wet age-related macular degeneration (AMD), a leading cause of vision loss. About 20 adults aged 50-89 who still need frequent eye injections will receive a one-time shot under the retina. The main goal is to check safety, but researchers will also look for signs that the treatment can reduce the need for repeat injections.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cincinnati Eye Institute
Cincinnati, Ohio, 45242, United States
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Retina Consultants of Texas
Bellaire, Texas, 77401, United States
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Sunnybrook Ophthalmology and Vision Services
Toronto, Ontario, M4N 3M5, Canada
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Vancouver Coastal Health Research Institute
Vancouver, British Columbia, V5Z 3N9, Canada
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Vitreous Retina Macula Specialists of Toronto
Toronto, Ontario, M8X 2X3, Canada
Conditions
Explore the condition pages connected to this study.