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New ultrasound technique could end the need for surgery to diagnose endometriosis

NCT ID NCT05523284

Diagnosis Sponsor: McMaster University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new ultrasound technique called SonoPODography (SPG) to diagnose superficial endometriosis, the most common form of the disease. Currently, diagnosis requires invasive surgery. The procedure involves injecting saline into the pelvis to create a clearer view of small lesions. Researchers will compare the accuracy of this method to standard surgery in 50 women with suspected superficial endometriosis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Saline-infused sonoPODgraphy (SPG) - a diagnostic ultrasound procedure using saline fluid
What this could lead to
If successful, this could provide a non-invasive way to diagnose superficial endometriosis, replacing the need for surgery.
What could go wrong
This is a small pilot study with only 50 participants, so results may not apply to everyone. The technique is new and needs more testing before it can be widely used.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All participants will be recruited from the McMaster Women's Health Clinic during routine pelvic evaluation using transvaginal ultrasound to assess the pelvic and abdominal cavity for any pathologies. Only participants with a uterus (assigned female at birth) will be eligible to join the study.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 Years of Age * Assigned Female at Birth * Confirmed or Suspected Case of Superficial Endometriosis * Willing and Able to Provide Informed Written Consent Exclusion Criteria: * Pre-Menarche or Post-Menopausal * No History of Vaginal Penetration / Intercourse * Concern for pre-malignancy or presence/history of malignancy * Known Bleeding Disorder * Presence of Deep or Ovarian Endometriosis

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Conditions

The condition(s) this trial relates to.

disease endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometriosis Endometriosis (diagnosis)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • McMaster University

    Hamilton, Ontario, L8S 4L8, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.