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New heart ablation tool tested in humans for first time

NCT ID NCT07503769

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests a new catheter that uses two types of energy (radiofrequency and pulsed field) to treat rapid heartbeats from the lower chambers. Ten adults with drug-resistant ventricular arrhythmias will receive the procedure. The main goal is to check safety and see if the abnormal rhythm stops right after treatment and at 3 months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dual-energy ablation catheter (radiofrequency and pulsed field)
What this could lead to
If successful, this could lead to a safer, more effective way to treat abnormal heart rhythms without long-term medication.
What could go wrong
This is a very early, small trial (10 people) focused on safety, not proof of effectiveness. The procedure carries risks like bleeding, heart damage, or arrhythmia recurrence.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 10 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient age ≥ 18 years and ≤ 75 years; * Clinically diagnosed with tachyarrhythmia, specifically idiopathic ventricular arrhythmia; * Recurrent disease with obvious symptoms prior to enrollment; * Failure to respond to or intolerance of at least one antiarrhythmic drug; * Fully understand the treatment plan, voluntarily sign the informed consent form, and agree to undergo the examinations, procedures and follow-up as required by the protocol. Exclusion Criteria: * Left ventricular ejection fraction (LVEF) ≤ 40% * History of ventricular flutter or ventricular fibrillation * Diagnosis of long QT syndrome or arrhythmogenic cardiomyopathy * Presence of structural heart disease or organic heart disease, including hypertrophic cardiomyopathy, dilated cardiomyopathy, ischemic cardiomyopathy, rheumatic heart disease, and congenital heart disease * Previous atrial septal repair or atrial myxoma * Carrying an active implantable device in the body (e.g., cardiac pacemaker, ICD, etc.) * NYHA functional class Ⅲ-Ⅳ * Patients with documented cerebrovascular disease within the past 6 months (including cerebral hemorrhage, stroke, transient ischemic attack) * Patients with cardiovascular events within the past 3 months (including acute myocardial infarction, percutaneous coronary intervention or coronary artery bypass grafting, prosthetic valve replacement or repair, atrial or ventricular incision) * Patients with acute or severe systemic infection * Patients with severe hepatic or renal disease, malignant tumor, or end-stage disease, who, in the investigator's judgment, may interfere with the treatment, evaluation, or compliance of this trial * Patients with significant bleeding tendency, hypercoagulable state, or severe hematological disorders * Patients who have participated in or are currently participating in other clinical trials within 3 months prior to enrollment * Patients with other conditions deemed inappropriate for participation in this trial by the investigator.

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Conditions

The condition(s) this trial relates to.

Ventricular Premature Complexes ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The First Affiliated Hospital of Ningbo University

    Ningbo, Zhejiang, China

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