New heart ablation tool tested in humans for first time
NCT ID NCT07503769
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tests a new catheter that uses two types of energy (radiofrequency and pulsed field) to treat rapid heartbeats from the lower chambers. Ten adults with drug-resistant ventricular arrhythmias will receive the procedure. The main goal is to check safety and see if the abnormal rhythm stops right after treatment and at 3 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dual-energy ablation catheter (radiofrequency and pulsed field)
- What this could lead to
- If successful, this could lead to a safer, more effective way to treat abnormal heart rhythms without long-term medication.
- What could go wrong
- This is a very early, small trial (10 people) focused on safety, not proof of effectiveness. The procedure carries risks like bleeding, heart damage, or arrhythmia recurrence.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient age ≥ 18 years and ≤ 75 years; * Clinically diagnosed with tachyarrhythmia, specifically idiopathic ventricular arrhythmia; * Recurrent disease with obvious symptoms prior to enrollment; * Failure to respond to or intolerance of at least one antiarrhythmic drug; * Fully understand the treatment plan, voluntarily sign the informed consent form, and agree to undergo the examinations, procedures and follow-up as required by the protocol. Exclusion Criteria: * Left ventricular ejection fraction (LVEF) ≤ 40% * History of ventricular flutter or ventricular fibrillation * Diagnosis of long QT syndrome or arrhythmogenic cardiomyopathy * Presence of structural heart disease or organic heart disease, including hypertrophic cardiomyopathy, dilated cardiomyopathy, ischemic cardiomyopathy, rheumatic heart disease, and congenital heart disease * Previous atrial septal repair or atrial myxoma * Carrying an active implantable device in the body (e.g., cardiac pacemaker, ICD, etc.) * NYHA functional class Ⅲ-Ⅳ * Patients with documented cerebrovascular disease within the past 6 months (including cerebral hemorrhage, stroke, transient ischemic attack) * Patients with cardiovascular events within the past 3 months (including acute myocardial infarction, percutaneous coronary intervention or coronary artery bypass grafting, prosthetic valve replacement or repair, atrial or ventricular incision) * Patients with acute or severe systemic infection * Patients with severe hepatic or renal disease, malignant tumor, or end-stage disease, who, in the investigator's judgment, may interfere with the treatment, evaluation, or compliance of this trial * Patients with significant bleeding tendency, hypercoagulable state, or severe hematological disorders * Patients who have participated in or are currently participating in other clinical trials within 3 months prior to enrollment * Patients with other conditions deemed inappropriate for participation in this trial by the investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The First Affiliated Hospital of Ningbo University
Ningbo, Zhejiang, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a puff of pot throw your heart out of rhythm?
- CT scan roadmap may improve heart ablation success