New drug combo could shrink deadly kidney cancer clots before surgery
NCT ID NCT05969496
First seen Apr 14, 2026 · Last updated May 22, 2026 · Updated 7 times
Summary
This study tests whether giving two drugs (pembrolizumab and axitinib) before surgery can shrink tumor clots in the main vein (inferior vena cava) for people with kidney cancer. About 17 adults with clear cell kidney cancer and a vein clot will receive the drugs for 12 weeks, then have surgery. The goal is to see if shrinking the clot makes surgery safer and improves long-term outcomes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Hilands Ranch Hospital
RECRUITINGHighlands Ranch, Colorado, 80129, United States
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Lone Tree Medical Center
RECRUITINGLone Tree, Colorado, 80124, United States
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University of Colorado Cancer Center
RECRUITINGAurora, Colorado, 80045, United States
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