Can a simple nebulizer mist stop Post-Surgery sore throat?
NCT ID NCT07491991
First seen Mar 29, 2026 · Last updated Jun 20, 2026 · Updated 12 times
Summary
This study tested whether spraying a mix of budesonide and lidocaine directly on the voice box during thyroid surgery could prevent the common problem of sore throat afterward. 96 adults having thyroid surgery with nerve monitoring were randomly assigned to get either the drug mist or a saltwater mist. The goal was to see if the drug combination reduced pain and other throat symptoms better than plain saline.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Qianfoshan Hospital, The First Hospital affiliated of Shandong First Medical University
Jinan, Shandong, 250000, China
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
budesonide combined with lidocaine
What this could lead to
If it works, this could provide a simple, non-invasive way to reduce sore throat after thyroid surgery, improving patient comfort and recovery.
What could go wrong
This is a small, single-center Phase 4 trial with only 96 participants. The benefit may be modest or not better than saline, and results may not apply to other surgeries.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.