SNIFF TEST: nasal swab may reveal lung disease severity
NCT ID NCT06661252
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study looked at whether substances in nasal fluid can help doctors objectively measure the severity of respiratory conditions like asthma, COPD, hayfever, and sinusitis. Researchers collected samples from 111 adults (including healthy volunteers) using a small nasal sampling device. The goal was to find a simple, non-invasive way to assess disease severity and quality of life, rather than relying only on symptoms or breathing tests.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
-
111 people
The number who actually took part.
- Started
-
Jan 2025
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Any individual aged 18+, either as a healthy control or a medically diagnosed sufferer of hayfever, asthma, rhinitis, chronic rhinosinusitis or chronic obstructive pulmonary disorder.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All participants: * 18 years of age or older * The participant must be able to comprehend and sign an approved Informed Consent Form and other applicable study documents. * Healthy volunteers: * No significant sinonasal/pulmonary symptoms or prior diagnoses of sinonasal/pulmonary conditions as determined by pre-enrolment questionnaires. * Case goup: * Participants must be previously diagnosed with rhinitis, chronic sinusitis, asthma, or COPD by a medical professional. Exclusion Criteria: * Less than 18 years of age at the time of enrolment. * Volunteers who are actively pregnant * Prior history of adverse reaction or contraindicated to diagnostic testing including fingerprick blood sampling, pulmonary testing, nasal swab/sampling. * Any other conditions limiting the volunteer's ability to complete study requirements in the judgement of the investigator/clinician * Any nasal anatomical issue or finding which may limit the safe insertion of the ABEL collection device, as determined by investigator/clinician * History of nasal surgery or trauma within the last 3 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Diag-Nose Medical
Notting Hill, Victoria, 3168, Australia
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