Fat injections and lasers join forces to fight stubborn scars
NCT ID NCT07679217
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study compares two treatments—nanofat injections and fractional CO2 laser—used alone or together for post-traumatic atrophic scars (depressed scars from injury). Sixty participants receive one of the three approaches. The goal is to see if combining both treatments improves scar appearance more than either alone, using skin exams and patient feedback.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Autologous nanofat injection and fractional CO2 laser
- What this could lead to
- If successful, combining nanofat with CO2 laser could offer a more effective, minimally invasive way to improve the appearance of traumatic scars.
- What could go wrong
- This is a small, early-stage study with no blinding, so results may not be conclusive. Individual results vary, and risks include infection or uneven healing.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female participants aged 12 years or older. * Presence of post-traumatic atrophic scar(s) of at least 6 months' duration. * No scar treatment received during the previous 6 months. * Willingness and ability to provide written informed consent (or assent with -parental/guardian consent for minors, according to local regulations). * Willingness to comply with study procedures and follow-up assessments. Exclusion Criteria: * Hemoglobin \<10 g/dL. * Active infection or viral skin disease. * Coagulopathy or hemophilia. * Current anticoagulant therapy. * Diabetes mellitus. * History of keloid formation. * History of malignancy or prior radiation therapy. * Immunosuppression. * Long-term systemic corticosteroid therapy. * Photosensitivity disorders. * Pregnancy or breastfeeding. * Renal or hepatic disease. * Systemic diseases affecting wound healing. * Thin patients with insufficient adipose tissue for adipose tissue harvesting. * Previous scar treatment within the preceding 6 months. * Use of systemic retinoids within the preceding 6 months. -Use of topical retinoids within the preceding 2 weeks.-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tanta University Hospital
Tanta, Gharbia Governorate, 31527, Egypt
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