Can your own fat help heal scars?
NCT ID NCT07763275
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study tests whether a single injection of nanofat—made from a person's own fat—can improve the appearance of atrophic scars caused by burns or trauma. Each participant has two similar scars: one gets the nanofat injection plus silicone gel, and the other gets only silicone gel. Over three months, researchers compare changes in scar appearance and patient satisfaction between the two sites.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Autologous nanofat injection (a procedure using the participant's own fat tissue) followed by topical silicone gel
- What this could lead to
- If effective, this could offer a minimally invasive way to improve the appearance of atrophic scars using a person's own fat.
- What could go wrong
- This is a small, early-stage trial with only 20 participants, so results may not apply broadly. The procedure carries typical risks of fat harvesting and injection, such as swelling or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Oct 2024
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older. * Presence of clinically diagnosed atrophic postburn or posttraumatic scars. * Scars were stable and mature at the time of enrollment. * Presence of two comparable scar areas suitable for the split-scar study design. * Scar sites were suitable for standardized clinical and photographic assessment. * Participants were willing to undergo a single session of autologous nanofat injection. * Participants were able to comply with the study visits and 3-month follow-up. * Written informed consent was obtained before participation. Exclusion Criteria * Hypertrophic scars or keloids. * Active infection, inflammation, ulceration, or dermatitis at the selected scar sites. * Previous procedural treatment of the selected scar sites that could affect study assessment. * Significant uncontrolled systemic disease that could interfere with wound healing or treatment. * Bleeding disorders or other contraindications to the fat-harvesting or injection procedure. * Pregnancy or breastfeeding. * Known allergy or intolerance to the topical silicone gel used in the study. * Inability to provide informed consent or comply with study follow-up. * Any medical condition considered by the investigator to pose an unacceptable risk or interfere with study evaluation. Exclusion Criteria: \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Benha faculty of medicine hospital
Banhā, Qaluybia, Egypt
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