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Dissolvable vs Non-Dissolvable stitches: which leaves a better scar on darker skin?

NCT ID NCT05408117

Symptom relief Sponsor: Melissa Pugliano-Mauro Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two types of stitches (dissolvable fast gut and non-dissolvable polypropylene) to see which leads to less scarring and pigment changes in people with darker skin. Each participant's wound is split in half, with one stitch type on each side, and scarring is measured at 7–10 days and 3 months. The goal is to find the best option for better cosmetic results in skin of color.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
suture type (dissolvable fast gut vs non-dissolvable polypropylene)
What this could lead to
If it works, this could help doctors choose the best suture to reduce dark or uneven scars in people with darker skin.
What could go wrong
This is a small, early-stage study with only 34 participants. Results may not apply to all scar types or body locations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 34 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2022

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18 years or older 2. Undergoing dermatologic surgery with planned standard elliptical excision with wound length of 3 cm or greater. Benign and malignant lesions will be included, including those that have undergone Mohs micrographic surgery prior to standard linear closure. All body sites will be included. 3. Able to give informed consent 4. Able to return for 3 month follow up 5. New Immigration Scale (NIS) skin color 4 or greater - The NIS is an 11 point scale, ranging from zero to 10, with zero representing albinism and 10 representing the darkest possible skin. Exclusion Criteria: 1. High-tension closures not amenable to 5-0 simple running epidermal sutures 2. Known allergy to suture material 3. Pregnant

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Conditions

The condition(s) this trial relates to.

severe cutaneous adverse reaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Scar

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • UPMC Presbyterian

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

  • UPMC Shadyside Place

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • UPMC St. Margaret

    RECRUITING

    Pittsburgh, Pennsylvania, 15215, United States

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