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Could antioxidant eye drops slow fuchs dystrophy? new trial underway

NCT ID NCT04440280

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 28 times

Summary

This study tests whether N-acetyl cysteine (NAC) eye drops can reduce harmful oxidative stress in the eyes of people with Fuchs endothelial corneal dystrophy (FECD). About 45 adults with advanced FECD who are already scheduled for corneal transplant surgery will use the drops for 28 days before their operation. Researchers will measure hydrogen peroxide levels in eye fluid to see if the drops lower oxidative damage.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts Eye and Ear Infirmary

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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